| UK | Opp | OTs | Date | School | Place | Event | All-Time |
| | | 11/4/2025 | Nicholls State | Lexington | BBN United Tipoff Classic | 0-0 |
| | | 11/7/2025 | Valparaiso | Lexington | BBN United Tipoff Classic | 2-0 |
| | | 11/11/2025 | Louisville | Louisville | | 40-17 |
| | | 11/14/2025 | Eastern Illinois | Lexington | BBN United Tipoff Classic | 0-0 |
| | | 11/18/2025 | Michigan State | New York | Champions Classic | 14-12 |
| | | 11/21/2025 | Loyola (MD) | Lexington | | 1-0 |
| | | 11/26/2025 | Tennessee Tech | Lexington | | 5-0 |
| | | 12/2/2025 | North Carolina | Lexington | ACC/SEC Challenge | 18-25 |
| | | 12/5/2025 | Gonzaga | Nashville | | 2-2 |
| | | 12/9/2025 | North Carolina - Central | Lexington | | 0-0 |
| | | 12/13/2025 | Indiana | Lexington | | 32-25 |
| | | 12/20/2025 | St. John's | Atlanta | CBS Sports Classic | 11-5 |
| | | 12/23/2025 | Bellarmine | Lexington | | 1-0 |
| | | 1/3/2026 | Alabama | Tuscaloosa | | 117-44 |
| | | 1/6/2026 | Missouri | Lexington | | 16-3 |
| | | 1/10/2026 | Mississippi State | Lexington | | 104-21 |
| | | 1/13/2026 | LSU | Baton Rouge | | 94-29 |
| | | 1/17/2026 | Tennessee | Knoxville | | 163-79 |
| | | 1/20/2026 | Texas | Lexington | | 2-1 |
| | | 1/24/2026 | Ole Miss | Lexington | | 111-15 |
| | | 1/27/2026 | Vanderbilt | Nashville | | 158-50 |
| | | 1/31/2026 | Arkansas | Fayetteville | | 36-15 |
| | | 2/3/2026 | Oklahoma | Lexington | | 5-0 |
| | | 2/7/2026 | Tennessee | Lexington | | 163-79 |
| | | 2/14/2026 | Florida | Gainesville | | 111-42 |
| | | 2/17/2026 | Georgia | Lexington | | 132-29 |
| | | 2/21/2026 | Auburn | Auburn | | 98-24 |
| | | 2/24/2026 | South Carolina | Columbia, SC | | 55-15 |
| | | 2/28/2026 | Vanderbilt | Lexington | | 158-50 |
| | | 3/3/2026 | Texas A & M | College Station | | 14-6 |
| | | 3/7/2026 | Florida | Lexington | | 111-42 |